Secondary amine - Names and Identifiers
Secondary amine - Introduction
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Secondary is an organic compound containing one amino group and two carbon atoms. Its structure can be represented by R-NH-R ', where R and R' represent organic groups. In contrast to primary amines, Secondary amines have two carbon atoms attached to the nitrogen atom in the molecule.
the nature of Secondary amine:
1. relatively volatile, often colorless liquid or gas.
2. There are basic sites on its two carbon atoms, which can react with acids to form salts.
3. The basicity of Secondary amine is weaker than primary amine, but stronger than secondary amine.
Purpose of Secondary amine:
1. As a solvent and reaction intermediate, it is widely used in organic synthesis.
2. In drug synthesis, it can be introduced as amine groups in drug molecules.
3. a coordination ligand for the catalyst.
Preparation of Secondary amine:
1. A common preparation method is obtained by a violent reaction of alcohol and ammonia. For example, Secondary can be obtained by the action of alcohol and ammonia.
2. Other preparation methods include barium dissolution by heating of hydrazide derivatives of primary amines and redox reactions.
Safety information for Secondary amine:
1. Secondary amine has a certain degree of irritation and corrosiveness, contact with the skin and eyes will cause irritation and damage.
2. Wear appropriate protective equipment during operation, including glasses, gloves and laboratory coats.
3. Avoid contact with oxidants and acids to prevent dangerous reactions.
4. storage should maintain a well-ventilated environment, and away from the source of fire and ignition.
Last Update：2024-04-09 19:43:38